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  2. Nucleosome - Wikipedia

    en.wikipedia.org/wiki/Nucleosome

    Nucleosome free region typically spans for 200 nucleotides in S. cerevisiae [43] Well-positioned nucleosomes form boundaries of NFR. These nucleosomes are called +1-nucleosome and −1-nucleosome and are located at canonical distances downstream and upstream, respectively, from transcription start site.

  3. Nuclear organization - Wikipedia

    en.wikipedia.org/wiki/Nuclear_Organization

    Each nucleosome consists of 8 histone protein subunits, around which roughly 147 DNA base pairs are wrapped in 1.67 left-handed turns. Nucleosomes provide about 7-fold initial linear compaction of DNA. [15] The concentration and specific composition of histones used can determine local chromatin structure.

  4. Eukaryotic chromosome structure - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_chromosome...

    The nucleosome is the basic unit of DNA condensation and consists of a DNA double helix bound to an octamer of core histones (2 dimers of H2A and H2B, and an H3/H4 tetramer). About 147 base pairs of DNA coil around 1 octamer, and ~20 base pairs are sequestered by the addition of the linker histone (H1), and various length of "linker" DNA (~0 ...

  5. Histone H2A - Wikipedia

    en.wikipedia.org/wiki/Histone_H2A

    Histones are proteins that package DNA into nucleosomes. [1] Histones are responsible for maintaining the shape and structure of a nucleosome. One chromatin molecule is composed of at least one of each core histones per 100 base pairs of DNA. [2] There are five families of histones known to date; these histones are termed H1/H5, H2A, H2B, H3 ...

  6. Histone H3.1 - Wikipedia

    en.wikipedia.org/wiki/Histone_H3.1

    Histone H3.1 is a protein in humans that is encoded by the H3C1 gene. [5] [6] [7] Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core ...

  7. Histone H2B type 1-C - Wikipedia

    en.wikipedia.org/wiki/Histone_H2B_type_1-C

    Histone H2B type 1-C/E/F/G/I is a protein that in humans is encoded by the HIST1H2BC gene. [ 5 ] [ 6 ] [ 7 ] Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes.

  8. HIST1H2BM - Wikipedia

    en.wikipedia.org/wiki/HIST1H2BM

    Histone H2B type 1-M is a protein that in humans is encoded by the HIST1H2BM gene. [ 5 ] [ 6 ] [ 7 ] Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes.

  9. HIST1H4K - Wikipedia

    en.wikipedia.org/wiki/HIST1H4K

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes.