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A mitotic inhibitor, microtubule inhibitor, or tubulin inhibitor, is a drug that inhibits mitosis, or cell division, and is used in treating cancer, gout, and nail fungus. These drugs disrupt microtubules , which are structures that pull the chromosomes apart when a cell divides.
Pages in category "Mitotic inhibitors" The following 32 pages are in this category, out of 32 total. ... Contact Wikipedia; Code of Conduct; Developers; Statistics;
Early Mitotic Inhibitor 1 (EMI1) is an important cell cycle regulator which ensures timely mitotic entry by primarily inhibiting Anaphase-Promoting Complex/Cyclosome (APC/C) activity. This protein is present in many organisms including Xenopus, Zebrafish, Drosophila (homologous protein: Rca1), and Humans (also often known as F-box only protein ...
Monomethyl auristatin E is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin.The linker to the monoclonal antibody is stable in extracellular fluid, but is cleaved by cathepsin once the conjugate has entered a tumor cell, thus activating the antimitotic mechanism.
ATC code M Musculo-skeletal system is a section of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. [1] [2] [3] [4]
3832 16551 Ensembl ENSG00000138160 ENSMUSG00000012443 UniProt P52732 Q6P9P6 RefSeq (mRNA) NM_004523 NM_010615 RefSeq (protein) NP_004514 NP_034745 Location (UCSC) Chr 10: 92.57 – 92.66 Mb Chr 19: 37.36 – 37.41 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Kinesin-like protein KIF11 is a molecular motor protein that is essential in mitosis. In humans it is coded for by the gene ...
Download QR code; Print/export Download as PDF; Printable version; In other projects ... Reversine is a potent inhibitor of the mitotic kinase Mps1 [4] ...
ATC code M04 Antigout preparations is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products. [1] [2] [3] Subgroup M04 is part of the anatomical group M Musculo-skeletal system. [4]