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Hunter syndrome is caused by a deficiency of the lysosomal enzyme iduronate-2-sulfatase (I2S). [2] [3] The lack of this enzyme causes heparan sulfate and dermatan sulfate to accumulate in all body tissues. [4] Hunter syndrome is the only MPS syndrome to exhibit X-linked recessive inheritance. [4] The symptoms of Hunter syndrome are comparable ...
Children with Hurler syndrome may appear normal at birth and develop symptoms over the first years of life. Symptoms vary between patients. [citation needed] One of the first abnormalities that may be detected is coarsening of the facial features; these symptoms can begin at 3–6 months of age. The head can be large with prominent frontal bones.
The drug Elmiron helps, for some patients, to prevent the formation of Hunner's ulcers by coating the bladder wall, thus making it harder for the acid in urine to irritate the bladder wall lining, which can lead to ulceration. Elmiron is a controversial medication within the interstitial cystitis community, with its efficacy questioned by many.
Signs and symptoms are also applied to physiological states outside the context of disease, as for example when referring to the signs and symptoms of pregnancy, or the symptoms of dehydration. Sometimes a disease may be present without showing any signs or symptoms when it is known as being asymptomatic . [ 13 ]
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A cast-iron ceiling fan made by Hunter, dating from the early 1980s. This model is called the "Original". The Hunter 'Original' (manufactured by the Hunter Fan Co.) is by far the most recognizable example of a cast-iron ceiling fan today. It has enjoyed the longest production run of any fan in history, dating from 1906 to the present day.
Melissa Bachman (born July 17, 1984) [1] is an American hunter, producer, and host of hunting television programs, currently of the cable television program Winchester Deadly Passion on the Sportsman Channel, Pursuit Channel, and Wild TV. [2] As a prominent female hunter, she has received personal online attacks.
Sporotrichosis, also known as rose handler's disease, [2] is a fungal infection that may be localised to skin, lungs, bone and joint, or become systemic. [ 2 ] [ 4 ] It presents with firm painless nodules that later ulcerate . [ 3 ]