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The mifepristone-misoprostol combination is, by far, the most recommended drug regimen for medical abortions, but other drug combinations are available. Misoprostol alone, without mifepristone, may be used in some circumstances for medical abortion, and has even been demonstrated to be successful in the second trimester. [37]
Several doctors with a private practice offer online consultations and e-prescriptions for a fee. [71] Honduras: Central America: N/A: N/A: After having been available one for cases of rape, it became legal for universal access in March 2023. [72] [73] Hong Kong: Asia [74] Iceland: Europe (LNG only) [75] India: Asia <33% [76] Indonesia: Asia ...
Misoprostol is used for the prevention of NSAID-induced gastric ulcers.It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell.
An abortion is one of the most common surgical procedures in Trinidad and Tobago, and most occur during the first 12 weeks of pregnancy. [3]According to the World Health Organization (WHO), an unsafe abortion is "a procedure for terminating an unwanted pregnancy either by persons lacking the necessary skills or in an environment lacking the minimal medical standards or both". [3]
Mifepristone combined with misoprostol is the preferred medication regimen for management of early pregnancy loss. While misoprostol alone can be used, the addition of a dose of mifepristone twenty-four hours before misoprostol administration improves treatment efficacy. [30]
Alprostadil and misoprostol are synthetic forms of prostaglandin E1 used as medications. Lubiprostone , a derivative of prostaglandin E1, is also used as a medication. [ 2 ] [ 3 ] Prostaglandin E 1 is a vasodilator .
The American College of Rheumatology and a Canadian consensus report both recommend GI-protective agents such as misoprostol be combined with long term NSAID therapy and a review concluded that diclofenac/misoprostol is a cost effective treatment in patients requiring long term NSAID therapy who are at increased risk of developing gastropathy. [4]
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