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A foreign body reaction (FBR) is a typical tissue response to a foreign body within biological tissue. [1] It usually includes the formation of a foreign body granuloma . [ 2 ] Tissue encapsulation of an implant is an example, as is inflammation around a splinter . [ 3 ]
[9] [24] In order for a biodegradable polymer to be used as a therapeutic, it must meet several criteria: 1) be non-toxic in order to eliminate foreign body response; 2) the time it takes for the polymer to degrade is proportional to the time required for therapy; 3) the products resulting from biodegredation are not cytotoxic and are readily ...
Protein adsorption influences the interactions that occur at the tissue-implant interface. Protein adsorption can lead to blood clots, the foreign-body response and ultimately the degradation of the device. In order to counter-act the effects of protein adsorption, implants are often coated with a polymer coating to decrease protein adsorption.
Chitosan has many excellent characteristics for biomedical science. Chitosan is biocompatible, it is highly bioactive, meaning it stimulates a beneficial response from the body, it can biodegrade which can eliminate a second surgery in implant applications, can form gels and films, and is selectively permeable. These properties allow for ...
A foreign-body giant cell is a collection of fused macrophages which are generated in response to the presence of a large foreign body. This is particularly evident with catheters , parasites , or biomaterials that are inserted into the body for replacement or regeneration of diseased or damaged tissues.
Host response is defined as the "response of the host organism (local and systemic) to the implanted material or device". Most materials will have a reaction when in contact with the human body. The success of a biomaterial relies on the host tissue's reaction with the foreign material.
Two major types of reaction occur in response to retained surgical foreign bodies. In the first type, an abscess may form with or without a secondary bacterial infection . The second reaction is an aseptic fibrinous response, resulting in tissue adhesions and encapsulation and eventually foreign body granuloma . [ 2 ]
A foreign body (FB) is any object originating outside the body of an organism. In machinery, it can mean any unwanted intruding object. In machinery, it can mean any unwanted intruding object. Most references to foreign bodies involve propulsion through natural orifices into hollow organs.