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Choriocarcinoma is a malignant, trophoblastic [1] cancer, usually of the placenta. It is characterized by early hematogenous spread to the lungs. It belongs to the malignant end of the spectrum in gestational trophoblastic disease (GTD). It is also classified as a germ cell tumor and may arise in the testis or ovary.
Bone metastasis, or osseous metastatic disease, is a category of cancer metastases that result from primary tumor invasions into bones. Bone-originating primary tumors such as osteosarcoma , chondrosarcoma , and Ewing sarcoma are rare; the most common bone tumor is a metastasis. [ 1 ]
Cannonball metastases are classically seen in renal cell carcinoma, [5] also seen in choriocarcinoma, endometrial cancer, [6] prostate cancer and some gastrointestinal malignancies. The presence of cannonball metastases is a hallmark of advanced systemic malignancy. Identification of these lesions often triggers search for primary tumor.
Gestational choriocarcinoma is a form of gestational trophoblastic neoplasia, which is a type of gestational trophoblastic disease (GTD), that can occur during pregnancy.It is a rare disease where the trophoblast, a layer of cells surrounding the blastocyst, undergoes abnormal developments, leading to trophoblastic tumors.
Hematological malignancies are malignant neoplasms ("cancer"), and they are generally treated by specialists in hematology and/or oncology. In some centers "hematology/oncology" is a single subspecialty of internal medicine while in others they are considered separate divisions (there are also surgical and radiation oncologists).
M describes distant metastasis (spread of cancer from one part of the body to another). The TNM staging system for all solid tumors was devised by Pierre Denoix of the Institut Gustave Roussy between 1943 and 1952, using the size and extension of the primary tumor, its lymphatic involvement, and the presence of metastases to classify the ...
Although choriocarcinoma is a highly malignant tumour and a life-threatening disease, it is very sensitive to chemotherapy. Virtually all women with non-metastatic disease are cured and retain their fertility; the prognosis is also very good for those with metastatic (spreading) cancer, in the early stages, but fertility may be lost.
The included cancer types are the ones causing most death as per data from the US in 2008. [1] Lung cancer, mainly to adrenal glands, brain, and bone [2] Breast cancer, mainly to bone, liver, lung and brain. [3] Colon cancer, mainly to liver. [4] Pancreatic cancer, mainly to liver and lungs. [5] Melanoma, mainly to brain [6]