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Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms , or combinations of organisms (for example, infection ).
Pharmacodynamics – what drugs do to the body and how. This includes not just the cellular and molecular aspects, but also more relevant clinical measurements. For example, not just the pharmacological actions of salbutamol , a beta2-adrenergic receptor agonist , but the respiratory peak flow rate of both healthy volunteers and patients.
According to the Journal Citation Reports, the journal has a 2014 impact factor of 5.03, ranking it second out of 30 journals in the category "Medical Laboratory Technology", [6] 17th out of 153 journals in the category "Medicine, General & Internal" [7] and 17th out of 123 journals in the category "Medicine, Research & Experimental" [8]
Clinical and Translational Science is a bimonthly peer-reviewed open-access medical journal covering translational medicine.It is published by Wiley-Blackwell and is an official journal of the American Society for Clinical Pharmacology and Therapeutics.
Pharmacokinetics is based on mathematical modeling that places great emphasis on the relationship between drug plasma concentration and the time elapsed since the drug's administration. Pharmacokinetics is the study of how an organism affects the drug, whereas pharmacodynamics (PD) is the study of
In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral of the concentration of a drug in blood plasma as a function of time (this can be done using liquid chromatography–mass spectrometry [1]).
The definition of the topical route of administration sometimes states that both the application location and the pharmacodynamic effect thereof is local. [3] In other cases, topical is defined as applied to a localized area of the body or to the surface of a body part regardless of the location of the effect.
Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects. [1] A biological target, also known as the site of action, can be binding proteins, ion channels, DNA, or a variety of other receptors.