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Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
[1] [4] [5] Methylprednisolone acetate was previously suspended with polyethylene glycol but is no longer formulated with this excipient due to concerns about possible toxicity. [6] [8] Depo methylprednisolone acetate is a depot injection and is absorbed slowly with a duration of weeks to months with a single intramuscular injection. [5]
Within the basin a Category 1 tropical cyclone is a tropical cyclone that has 10-minute mean maximum sustained wind speeds of 33–47 knots (61–87 km/h; 38–54 mph) on the Australian tropical cyclone intensity scale. [1] [2] A named storm could also be classified as a Category 1 tropical cyclone if it is estimated, to have 1-minute mean ...
Category 1 is the first category on the Saffir–Simpson hurricane wind scale and the Australian tropical cyclone intensity scale. The following lists show tropical cyclones that have reached that intensity in Earth's ocean basins. List of Category 1 Atlantic hurricanes; List of Category 1 Pacific hurricanes
Hurricane Hone at peak intensity on August 25, 2024. Hone is the most recent Category 1 hurricane in the Pacific. Category 1 is the lowest classification on the Saffir–Simpson hurricane wind scale, and categorizes tropical cyclones with 1-minute maximum sustained winds between 64 and 82 knots (74 and 94 mph; 119 and 152 km/h; 33 and 42 m/s).
Hurricane Oscar is the most recent Category 1 hurricane as of October 2024.. Category 1 is the lowest hurricane classification on the Saffir–Simpson scale.When a storm's wind speed is between 64 knots (74 mph; 119 km/h; 33 m/s) and 82 knots (95 mph; 153 km/h; 42 m/s), it is classified as a Category 1. [1]
As one can see, it would take many days for the total amount of drug within the body to come close to 1 gram (1000 mg) and achieve its full therapeutic effect. For a drug such as this, a doctor might prescribe a loading dose of one gram to be taken on the first day. That immediately gets the drug's concentration in the body up to the ...
Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [ 1 ] When a drug has a narrow therapeutic index , titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [ 2 ]