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4018 n/a Ensembl ENSG00000198670 n/a UniProt P08519 n/a RefSeq (mRNA) NM_005577 n/a RefSeq (protein) n/a n/a Location (UCSC) Chr 6: 160.53 – 160.66 Mb n/a PubMed search n/a Wikidata View/Edit Human Lipoprotein(a) is a low-density lipoprotein variant containing a protein called apolipoprotein(a). Genetic and epidemiological studies have identified lipoprotein(a) as a risk factor for ...
“High lipoprotein(a) impacts one in five globally…And it's not just the individual, it's the families, because each child born to someone with it has a 50% chance of inheriting it.”
“High lipoprotein(a) impacts 1 in 5 globally… And it's not just the individual, it's the families, because each child born to someone with it has a 50% chance of inheriting it.”
Lipoprotein(a) (LPA) is a lipoprotein particle of a certain phenotype; High-density lipoproteins (HDL) collect fat molecules from the body's cells/tissues and take them back to the liver. HDLs are sometimes referred to as "good" lipoprotein because higher concentrations correlate with low rates of atherosclerosis progression and/or regression.
and LDL-C reduction is indicated if the count in mg/dL is over... High, meaning a 20% or greater risk of heart attack within 10 years, or an extreme risk factor 70 [54] 100 [54] moderately high, meaning a 10-20% risk of heart attack within 10 years and more than 2 heart attack risk factors 100 [54] 130 [54]
About 13% — roughly 3,600 participants — had either a heart attack or stroke, had surgery to fix a narrowed or blocked artery, or died from heart disease over the 30-year follow-up period.
Apolipoprotein E (apoE) plays an important role in the transport and uptake of cholesterol by way of its high affinity interaction with lipoprotein receptors, including the low-density lipoprotein (LDL) receptor. ApoE is the major lipoprotein in the central nervous system.
Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood. [1] It is a form of hyperlipidemia (high levels of lipids in the blood), hyperlipoproteinemia (high levels of lipoproteins in the blood), and dyslipidemia (any abnormalities of lipid and lipoprotein levels in the blood).