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The enzyme pyrogallol hydroxytransferase uses benzene-1,2,3,5-tetrol and benzene-1,2,3-triol (pyrogallol), whereas its two products are benzene-1,3,5-triol ...
It is a metabolite in the degradation of 3,4,5-trihydroxybenzoate (gallic acid) by Eubacterium oxidoreducens. [ 1 ] The enzyme pyrogallol hydroxytransferase uses 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene ( pyrogallol ), whereas its two products are 1,3,5-trihydroxybenzene ( phloroglucinol ) and 1,2,3,5-tetrahydroxybenzene.
Thus, the two substrates of this enzyme are 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene (pyrogallol), whereas its two products are 1,3,5-trihydroxybenzene (phloroglucinol) and 1,2,3,5-tetrahydroxybenzene. This enzyme participates in benzoic acid degradation via CoA ligation.
As examples, DNA damaging effects have been reported for acrolein, [14] formaldehyde, [15] and acrylonitrile. [16] Breast cancer is the second most frequent cancer worldwide on a yearly basis [(1.38 million cases, 10.9% of all cancer cases), and ranks 5th as cause of death (458,000, 6.1% of all cancer deaths)]. [12]
Hydroxyquinol is a common intermediate in the biodegradation of many aromatic compounds. These substrates include monochlorophenols, dichlorophenols, and more complex species such as the pesticide 2,4,5-T. [5]
The enzyme pyrogallol hydroxytransferase uses 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene (pyrogallol) to produce 1,3,5-trihydroxybenzene (phloroglucinol) and 1,2,3,5-tetrahydroxybenzene. It is found in the bacterium species Pelobacter acidigallici .
P. acidigallici is able to degrade trihydroxybenzenes. [1] The enzyme pyrogallol hydroxytransferase uses 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene , whereas its two products are 1,3,5-trihydroxybenzene (phloroglucinol) and 1,2,3,5-tetrahydroxybenzene. This enzyme can be found in P. acidigallici. [2]
The 3 substrates of this enzyme are 2-hydroxy-1,4-benzoquinone, NADH, and H +, whereas its two products are 1,2,4-trihydroxybenzene and NAD +. This enzyme participates in gamma-hexachlorocyclohexane degradation and 1,4-dichlorobenzene degradation .