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The Infectious Diseases Society of America recommends 5–10 days of treatment with levofloxacin or 3–5 days of treatment with azithromycin; however, patients that are immunocompromised or have a severe disease may require an extended course of treatment. [42] Enzymes in the iron uptake pathway have been also suggested as important drug ...
This is a list of Legionnaires' disease outbreaks; Legionnaire's is a potentially fatal infectious disease caused by gram negative, aerobic bacteria belonging to the genus Legionella. [ 1 ] [ 2 ] The first reported outbreak was in Philadelphia, Pennsylvania in 1976 during a Legionnaires Convention at the Bellevue-Stratford Hotel .
The fatality rate of Legionnaires' disease has ranged from 5–30% during various outbreaks and approaches 50% for nosocomial infections, especially when treatment with antibiotics is delayed. [38] Hospital-acquired Legionella pneumonia has a fatality rate of 28%, and the principal source of infection in such cases is the drinking-water ...
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High levels of Legionella bacteria were found in a cooling tower at Embassy Suites Napa Valley, though none of the patients had visited the hotel. Outbreak of Legionnaires' disease in Napa County ...
Pontiac fever is known to have a short incubation period of 1 to 3 days. No fatalities have been reported and cases resolve spontaneously without treatment. [8] It is often not reported. [9] Age, gender, and smoking do not seem to be risk factors. Pontiac fever seems to affect young people in the age medians of 29 to 32.
Ionization can be an effective process to control Legionella in potable water distribution systems found in health facilities, hotels, nursing homes, and large buildings. . In 2003, ionization became the first such hospital disinfection process to have fulfilled a proposed four-step modality evaluation; by then it had been adopted by over 100 hospitals.
The first-line options when Legionella is the causative agent are macrolides and fluoroquinolones. Azithromycin , a type of macrolide, is the preferred choice. For patients with mild illness, the treatment course usually lasts about 10-14 days, although most symptoms tend to improve within the first 3-5 days of starting the antibiotics.