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Sonic the Hedgehog, [a] trademarked Sonic The Hedgehog, [1] is a blue anthropomorphic hedgehog and the main protagonist of the series. Developed as a replacement for their existing Alex Kidd mascot, as well as Sega's response to Mario, his first appearance was in the arcade game Rad Mobile as a cameo, before making his official debut in Sonic the Hedgehog (1991).
After several years of research and creating prototypes, the Sonicare toothbrush was introduced in 1992. [9] In 1995, GEMTech changed its name to Optiva Corporation. [9] The company was originally headquartered in Bellevue, Washington, and moved to Snoqualmie, Washington, in 1999. The 176,000 square feet (16,400 m 2) plant in Snoqualmie was ...
Dental caries (cavities), described as "tooth decay", is an infectious disease which damages the structures of teeth. [43] The disease can lead to pain, tooth loss, and infection. Dental caries has a long history, with evidence showing the disease was present in the Bronze, Iron, and Middle ages but also prior to the neolithic period. [44]
This is a dental practitioner view, so tooth number 1, the rear upper tooth on the patient's right, appears on the left of the chart. The Universal Numbering System, sometimes called the "American System", is a dental notation system commonly used in the United States. [1][2] Most of the rest of the world uses the FDI World Dental Federation ...
Sonic the Hedgehog (character) Sonic the Hedgehog[b] is a character created by the Japanese game developers Yuji Naka and Naoto Ohshima. He is the star of the Sonic the Hedgehog franchise and the mascot of the Japanese video game company Sega. Sonic is an anthropomorphic blue hedgehog who can run at supersonic speed.
Crystal structure of Wnt8 (rainbow coloring) bound to the cysteine rich domain of Frizzled8 (green). Wnt comprises a diverse family of secreted lipid-modified signaling glycoproteins that are 350–400 amino acids in length. [11] The lipid modification of all Wnts is palmitoleoylation of a single totally conserved cysteine residue. [12]
Sonic the Hedgehog[ a ] is a video game series and media franchise created by the Japanese developers Yuji Naka, Naoto Ohshima, and Hirokazu Yasuhara for Sega. The franchise follows Sonic, an anthropomorphic blue hedgehog who battles the evil Doctor Eggman, a mad scientist. The main Sonic the Hedgehog games are platformers mostly developed by ...
Georgia, officially the State of Georgia, is a state in the Southeastern region of the United States.It borders Tennessee to the northwest, North Carolina to the north, South Carolina to the northeast, the Atlantic Ocean to the southeast, Florida to the south, and Alabama to the west.