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Cell-count distribution featuring cellular differentiation for three types of cells (progenitor , osteoblast , and chondrocyte ) exposed to pro-osteoblast stimulus. [1] Cellular differentiation is the process in which a stem cell changes from one type to a differentiated one. [2][3] Usually, the cell changes to a more specialized type.
Cell potency is a cell's ability to differentiate into other cell types. [1] [2] The more cell types a cell can differentiate into, the greater its potency.Potency is also described as the gene activation potential within a cell, which like a continuum, begins with totipotency to designate a cell with the most differentiation potential, pluripotency, multipotency, oligopotency, and finally ...
Cell differentiation is the process whereby different functional cell types arise in development. For example, neurons, muscle fibers and hepatocytes (liver cells) are well known types of differentiated cells. Differentiated cells usually produce large amounts of a few proteins that are required for their specific function and this gives them ...
Anaplasia is defined as cells being in an undifferentiated state and it is often associated with cancer. Often this loss of mature cell markers or morphology can be due to dedifferentiation, [11] but it is sometimes used to refer to cells with incomplete differentiation presenting large variety in size and shape. [18]
Multicellular organism. The nematode Caenorhabditis elegans stained to highlight the nuclei of its cells. A multicellular organism is an organism that consists of more than one cell, unlike unicellular organisms. [1] All species of animals, land plants and most fungi are multicellular, as are many algae, whereas a few organisms are partially ...
Disruption of asymmetric cell division leads to aberrant self-renewal and impairs differentiation, and could therefore constitute an early step in the tumorogenic transformation of stem and progenitor cells. In normal non-tumor stem cells, a number of genes have been described which are responsible for pluripotency, such as Bmi-1, Wnt and Notch.
Germ-Soma Differentiation is the process by which organisms develop distinct germline and somatic cells. The development of cell differentiation has been one of the critical aspects of the evolution of multicellularity and sexual reproduction in organisms. Multicellularity has evolved upwards of 25 times, [1] and due to this there is great ...
Transdifferentiation. Transdifferentiation, also known as lineage reprogramming, [1] is the process in which one mature somatic cell is transformed into another mature somatic cell without undergoing an intermediate pluripotent state or progenitor cell type. [2] It is a type of metaplasia, which includes all cell fate switches, including the ...