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Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.
Are Diabetes Weight Loss Drugs Safe? Generally speaking, GLP-1s, GIP/GLP-1s, and metformin are considered safe and effective when used as prescribed. That said, no medication is without side effects.
Another medication, orlistat, is widely available and approved for long-term use. Its use produces modest weight loss, with an average of 2.9 kg (6.4 lb) at 1 to 4 years, but there is little information on how these medications affect longer-term complications of obesity.
Telmisartan was patented in 1991 and came into medical use in 1999. [7] It is available as a generic medication . [ 8 ] In 2022, it was the 228th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
More studies are needed, but long-term semaglutide use appears to be safe. A 2022 study — funded by Novo Nordisk, the manufacturer of Ozempic and Wegovy — found that taking semaglutide for two ...
"I think the amount of good done by these medications by helping people lose weight and improve their cardiovascular system — and it might have long-term benefits in a lot of other areas as well ...
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