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Early-onset Alzheimer's disease strikes earlier in life, defined as before the age of 65 (usually between 30 and 60 years of age). [ medical citation needed ] Early signs of AD include unusual memory loss, particularly in remembering recent events and the names of people and things ( logopenic primary progressive aphasia ).
Early onset dementia is less common than late onset dementia, the former accounting for approximately 10% of dementias globally. [3] Recent studies estimate the prevalence of early onset dementia to be approximately 3.55 million people aged 30–64 worldwide, and will triple by 2050. [6] with an incidence of 119 per 100,000 individuals. [1]
Again, these problems go beyond squinting at the television from across the room or writing the wrong date on your checks, which are all normal parts of aging; early Alzheimer's symptoms would ...
The symptoms of early dementia usually include memory difficulty, but can also include some word-finding problems, and problems with executive functions of planning and organization. [53] Managing finances may prove difficult. Other signs might be getting lost in new places, repeating things, and personality changes. [54]
New research published in Neurology found that cognitively healthy people who self-reported memory problems had early signs of Alzheimer’s disease, such as higher tau tangles, in their brains.
Frontotemporal dementia (FTD) is an early onset disorder that mostly occurs between the ages of 45 and 65, [13] but can begin earlier, and in 20–25% of cases onset is later. [11] [14] Men and women appear to be equally affected. [15] It is the most common early presenting dementia. [16]
When the disease is caused by autosomal dominant variants, it is known as early onset familial Alzheimer's disease, which is rarer and has a faster rate of progression. [17] Less than 5% of sporadic Alzheimer's disease have an earlier onset, [17] and early-onset Alzheimer's is about 90% heritable.
MCI may include both memory and non-memory neurocognitive impairments. [3] About 50 percent of people diagnosed with MCI have Alzheimer's disease and go on to develop Alzheimer's dementia within five years. MCI can also serve as an early indicator for other types of dementia, although MCI may also remain stable or remit. [4]
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