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[1] [9] People with latent TB do not spread the disease. [1] Active infection occurs more often in people with HIV/AIDS and in those who smoke. [1] Diagnosis of active TB is based on chest X-rays, as well as microscopic examination and culture of bodily fluids. [10] Diagnosis of latent TB relies on the tuberculin skin test (TST) or blood tests ...
The blood tests QuantiFERON-TB Gold In-Tube and T-SPOT.TB use these antigens to detect people with tuberculosis. Lymphocytes from the patient's blood are incubated with the antigens. These tests are called interferon γ tests and are not equivalent. [19] If the patient has been exposed to tuberculosis before, T lymphocytes produce interferon γ ...
The equivalent Mantoux test positive levels done with 10 TU (0.1 mL 100 TU/mL, 1:1000) are 0–4 mm induration (Heaf 0-1) 5–14 mm induration (Heaf 2) >15 mm induration (Heaf 3-4) The Mantoux test is preferred in the United States for the diagnosis of tuberculosis; multiple puncture tests, such as the Heaf test and Tine test, are not recommended.
In fact, "it isn't easy to catch TB. You need consistent exposure to the contagious person for a long time. For that reason, you're more likely to catch TB from a relative than a stranger." [7] If a person had latent tuberculosis, they do not have active/contagious tuberculosis. Once exposed, people very often have latent tuberculosis.
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A patient is expected to be free from all living TB bacteria after six months of therapy in Pulmonary TB or 8-10 months in Miliary TB. [citation needed] Latent tuberculosis or latent tuberculosis infection (LTBI) is treated with three to nine months of isoniazid alone. This long-term treatment often risks the development of hepatotoxicity. A ...
The first test is read 48–72 hours after injection. If the first test is positive, consider the person infected. If the first test is negative, give a second test one to three weeks after the first injection. The second test is read 48–72 hours after injection. If the second test is positive, consider the person infected in the distant past ...
Since this one’s a blood test, you don’t need to show up again to have the test read like you do with the PPD. Also, the IGRA is more specific to TB rather than other types of mycobacterial infections and is unlikely to be positive as a result of having BCG vaccine in the past, a vaccine that protects against TB.