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Ventilation is the movement of gas during breathing, and perfusion is the process of pulmonary blood circulation, which delivers oxygen to body tissues. [2] Anatomically, the lung structure, alveolar organization , and alveolar capillaries contribute to the physiological mechanism of ventilation and perfusion. [ 1 ]
Gas exchange thus becomes highly inefficient leading to hypoxemia, as measured by arterial oxygenation. A ventilation perfusion scan or lung scintigraphy can be used to diagnose areas of lungs being ventilated but not adequately perfused.
Gas exchange is the physical process by which gases move passively by diffusion across a surface. For example, this surface might be the air/water interface of a water body, the surface of a gas bubble in a liquid, a gas-permeable membrane, or a biological membrane that forms the boundary between an organism and its extracellular environment.
Gas exchange takes place in the gills which consist of thin or very flat filaments and lammellae which expose a very large surface area of highly vascularized tissue to the water. Other animals, such as insects, have respiratory systems with very simple anatomical features, and in amphibians, even the skin plays a vital role in gas exchange.
Exchange of gases in the lung occurs by ventilation and perfusion. [1] Ventilation refers to the in-and-out movement of air of the lungs and perfusion is the circulation of blood in the pulmonary capillaries. [1] In mammals, physiological respiration involves respiratory cycles of inhaled and exhaled breaths.
Acute respiratory acidosis occurs when an abrupt failure of ventilation occurs. This failure in ventilation may be caused by depression of the central respiratory center by cerebral disease or drugs, inability to ventilate adequately due to neuromuscular disease (e.g., myasthenia gravis, amyotrophic lateral sclerosis, Guillain–Barré syndrome, muscular dystrophy), or airway obstruction ...
Real-time magnetic resonance imaging of the human thorax during breathing X-ray video of a female American alligator while breathing. Breathing (spiration [1] or ventilation) is the rhythmical process of moving air into and out of the lungs to facilitate gas exchange with the internal environment, mostly to flush out carbon dioxide and bring in oxygen.
Assessing and monitoring blood gas levels is the most accurate means to identify a state of respiratory compromise in patients. ABG testing does however require an arterial blood sample, which is more invasive and uncomfortable for patients than a pulse oximetry reading that uses a reading based on light and color. [7]