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  2. Collagen gel contraction assay - Wikipedia

    en.wikipedia.org/wiki/Collagen_gel_contraction_assay

    The collagen gel contraction assay is an in vitro model of wound contraction. It is performed using the dermal equivalent model, which consists of dermal fibroblasts seeded into a collagen gel. [ 1 ]

  3. Artificial skin - Wikipedia

    en.wikipedia.org/wiki/Artificial_skin

    In one case, however, a particular type of collagen graft led to significant delay of wound closure. [6] Careful study of histology samples revealed that grafts that delayed wound closure induced the synthesis of new dermis de novo at the injury site, instead of forming scar, which is the normal outcome of the spontaneous wound healing response.

  4. Hypertrophic scar - Wikipedia

    en.wikipedia.org/wiki/Hypertrophic_scar

    Mechanical tension on a wound has been identified as a leading cause for hypertrophic scar formation. [3] When a normal wound heals, the body produces new collagen fibers at a rate which balances the breakdown of old collagen. Hypertrophic scars are red to brown and thick and may be itchy or painful.

  5. Dermis - Wikipedia

    en.wikipedia.org/wiki/Dermis

    The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...

  6. Wound healing - Wikipedia

    en.wikipedia.org/wiki/Wound_healing

    Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.

  7. Ground substance - Wikipedia

    en.wikipedia.org/wiki/Ground_substance

    Link proteins such as vinculin, spectrin and actomyosin stabilize the proteoglycans and organize elastic fibers in the ECM. [2] Changes in the density of ground substance can allow collagen fibers to form aberrant cross-links. [2] Loose connective tissue is characterized by few fibers and cells, and a relatively large amount of ground substance.

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    mail.aol.com/?offerId=netscapeconnect-en-us

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  9. Catgut suture - Wikipedia

    en.wikipedia.org/wiki/Catgut_suture

    Catgut Chrome (B Braun) suture is a variant treated with chromic acid salts. This treatment produces roughly twice the stitch-holding time of plain catgut, but greater tissue inflammation occurs.