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  2. Sticky and blunt ends - Wikipedia

    en.wikipedia.org/wiki/Sticky_and_blunt_ends

    The simplest DNA end of a double stranded molecule is called a blunt end. Blunt ends are also known as non-cohesive ends. In a blunt-ended molecule, both strands terminate in a base pair. Blunt ends are not always desired in biotechnology since when using a DNA ligase to join two molecules into one, the yield is significantly lower with blunt ...

  3. Ligation (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Ligation_(molecular_biology)

    Restriction enzymes can generate a wide variety of ends in the DNA they digest, but in cloning experiments most commonly-used restriction enzymes generate a 4-base single-stranded overhang called the sticky or cohesive end (exceptions include NdeI which generates a 2-base overhang, and those that generate blunt ends). These sticky ends can ...

  4. Lambda phage - Wikipedia

    en.wikipedia.org/wiki/Lambda_phage

    The repressor found in the phage lambda is a notable example of the level of control possible over gene expression by a very simple system. It forms a 'binary switch' with two genes under mutually exclusive expression, as discovered by Barbara J. Meyer .

  5. Immunoglobulin light chain - Wikipedia

    en.wikipedia.org/wiki/Immunoglobulin_light_chain

    If the lymph node or similar tissue is reactive, or otherwise benign, it should possess a mixture of kappa positive and lambda positive cells. If, however, one type of light chain is significantly more common than the other, the cells are likely all derived from a small clonal population, which may indicate a malignant condition, such as B-cell ...

  6. Son Dead, Mother in Critical Condition After Home Invasion in ...

    www.aol.com/son-dead-mother-critical-condition...

    A home invasion in an upscale Philadelphia suburb turned fatal over the weekend after a suspect broke into a home in Lower Merion Township at 2:20 a.m. on Sunday, Dec. 8, the Montgomery County ...

  7. Fla. Man Accused of Beating Golfer to Death With Golf Clubs ...

    www.aol.com/fla-man-accused-beating-golfer...

    A Florida man is accused of beating another man to death with golf clubs on a course in Palm Beach County. A probable cause affidavit filed by the Palm Beach Gardens Police Department obtained by ...

  8. Integration host factor - Wikipedia

    en.wikipedia.org/wiki/Integration_host_factor

    When the Integration Host Factor was first discovered, it was only known for the site-specific recombination of bacteriophage. [4] This is all we knew for a while but through another article, we were able to find that with further research, IHF plays a key role in the scope of physiological processes of E. Coli, including site-specific recombination activities, phage packaging and partitioning ...

  9. Joey Galloway: Indiana should bench QB Kurtis Rourke vs ... - AOL

    www.aol.com/joey-galloway-indiana-bench-qb...

    ESPN's Joey Galloway on Tuesday said Indiana football shouldn't play quarterback Kurtis Rourke vs. Ohio State to keep its CFP path intact.