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Legionella is a genus of gram-negative bacteria that can be seen using a silver stain or grown in a special media that contains cysteine, an amino acid.It is known to cause legionellosis [3] (all illnesses caused by Legionella) including a pneumonia-type illness called Legionnaires' disease and a mild flu-like illness called Pontiac fever. [3]
Legionella pneumophila, the primary causative agent for Legionnaire's disease, is an aerobic, pleomorphic, flagellated, non-spore-forming, Gram-negative bacterium. [1] [2] L. pneumophila is a intracellular parasite that preferentially infects soil amoebae and freshwater protozoa for replication.
Examples of facultative intracellular bacteria include members of the genera Brucella, Legionella, Listeria, and Mycobacterium.These bacteria invade the human body and replicate inside the cells, evading the immune system and causing disease by disrupting the human's cells normal function.
Legionella spp. enter the lungs either by aspiration of contaminated water or inhalation of aerosolized contaminated water or soil. In the lung, the bacteria are consumed by macrophages, a type of white blood cell, inside of which the Legionella bacteria multiply, causing the death of the macrophage. Once the macrophage dies, the bacteria are ...
The New Hampshire Department of Health and Human ... Legionnaires' disease is caused by inhaling water droplets contaminated with the Legionella bacteria. The bacteria can grow in water droplets ...
Legionnaires’ disease is a type of pneumonia caused by Legionella bacteria. The bacteria can grow in any area where water sits for a long time, according to Dr. Andrew Handel, a pediatric ...
In order to grow, they need nutrients that might be scarce in their free form in the cell. To study the mechanism that intracellular parasites use to obtain nutrients, Legionella pneumophila , a bacterial facultative intracellular parasite, has been used as a model.
The legionella bacteria responsible for the disease lives and multiplies in water areas like hot tubs, air conditioners, mist sprayers in grocery store produce departments, and water systems.