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Fluphenazine, sold under the brand name Prolixin among others, is a high-potency typical antipsychotic medication. [2] It is used in the treatment of chronic psychoses such as schizophrenia , [ 2 ] [ 3 ] and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine . [ 4 ]
Dosage T max t 1/2 single t 1/2 multiple logP c ... Fluphenazine decanoate: Prolixin Decanoate: Typical: ... All by intramuscular injection.
If a scheduled injection of either haloperidol decanoate or fluphenazine decanoate is missed, recommendations for administering make-up injectable dose(s) or providing antipsychotics to be taken by mouth vary by, e.g., how long ago the last injection was and how many previous injections the person has received (i.e., if steady state levels of ...
It is administered by depot injection into muscle. [2] ... Dosage T max t 1/2 single t 1/2 multiple logP c ... Fluphenazine decanoate: Prolixin Decanoate: Typical:
Dosage T max t 1/2 single t 1/2 multiple logP c ... Fluphenazine decanoate: Prolixin Decanoate: Typical: ... All by intramuscular injection.
The i.m.-injections are appropriate for a few days, but oral treatment should start as soon as possible. In many countries, depot forms of perphenazine exist (as perphenazine enanthate and perphenazine decanoate). One injection works for 1 to 4 weeks depending on the dose of the depot-injection.
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Use of any antipsychotic is associated with reductions in brain tissue volumes, [6] [7] including white matter reduction, [8] an effect which is dose-dependent and time-dependent. [ 6 ] [ 7 ] A recent controlled trial suggests that second generation antipsychotics [ 9 ] combined with intensive psychosocial therapy [ 10 ] may potentially prevent ...