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Fluphenazine, sold under the brand name Prolixin among others, is a high-potency typical antipsychotic medication. [2] It is used in the treatment of chronic psychoses such as schizophrenia , [ 2 ] [ 3 ] and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine . [ 4 ]
The first long-acting (depot) injections were antipsychotics fluphenazine and haloperidol. [2] The concept of a depot injection arose before 1950, and originally was used to describe antibiotic injections that lasted longer to allow for less frequent administration. [4]
Note: All by intramuscular injection. Footnotes: a = Microcrystalline or nanocrystalline aqueous suspension . b = Low- viscosity vegetable oil (specifically fractionated coconut oil with medium-chain triglycerides ).
Another traditional antipsychotic used in treating Tourette's is fluphenazine (brand name Prolixin), although the evidence supporting its use is less than that of haloperidol and pimozide. [4] The classes of medication with proven efficacy in treating tics—typical and atypical neuroleptics—can have long-term and short-term adverse effects. [4]
Together, these modifications prevent the active medications from being released immediately upon injection, attaining a slow release of the active medications (note, though, that the fluphenazine decanoate product is unique for reaching peak fluphenazine blood levels within 24 hours after administration [19]). [18]
A New York appeals court judge has denied President-elect Donald Trump's request to delay the Jan. 10 sentencing in his criminal hush money case. Trump’s sentencing will proceed as planned on ...
WASHINGTON (Reuters) -A U.S. Justice Department watchdog report released on Thursday debunked claims by far-right conspiracy theorists who falsely alleged that FBI operatives were secretly ...
Outcome Findings in words Findings in numbers Quality of evidence Global outcome Leaving the study early Follow up: 6 weeks to 5 months: Fluspirilene decanoate may increase the risk of leaving the study (reasons not specified), but, the difference is not clear between people given fluspirilene decanoate and those receiving oral antipsychotics.