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A granuloma is an aggregation of macrophages (along with other cells) that forms in response to chronic inflammation.This occurs when the immune system attempts to isolate foreign substances that it is otherwise unable to eliminate. [1]
In humans, eosinophilic granulomas are considered as a benign tumors that occurs mainly in children and adolescents. EG is a quite rare condition, and its incidence is higher in white than in black population, also slightly more affecting males than females.
[3] [4] It has been noted that these granulomas have the propensity to manifest on any organ or soft tissue. [3] Plasma cell granulomas are generally found to be benign, but in some cases, the granulomas have the ability to initiate malignancy and become symptomatic regardless of location or size. [3]
The most common benign coin lesion is a granuloma (inflammatory nodule), for example due to tuberculosis or a fungal infection, such as Coccidioidomycosis. [6] Other infectious causes include a lung abscess , pneumonia (including pneumocystis pneumonia ) or rarely nocardial infection or worm infection (such as dirofilariasis or dog heartworm ...
Central giant-cell granuloma (CGCG) is a localised benign condition of the jaws.It is twice as common in females and is more likely to occur before age 30. Central giant-cell granulomas are more common in the anterior mandible, often crossing the midline and causing painless swellings.
A pyogenic granuloma, is a small benign vascular tumor that primarily involves the skin (88.2%) and mucous membranes. [6] Pyogenic granuloma appears as a red macule that grows rapidly, turns into a papule and eventually becomes pedunculated, being attached to a narrow stalk. [8]
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The primary method for treatment is surgical, not medical. Radiation and chemotherapy are not needed for benign lesions and are not effective for malignant lesions. Benign granular cell tumors have a recurrence rate of 2% to 8% when resection margins are deemed clear of tumor infiltration. When the resection margins of a benign granular cell ...