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Clonidine's blood pressure lowering effects are due to stimulation of presynaptic α 2 autoreceptors in the CNS which suppress sympathetic outflow. Mirtazapine itself blocks these same α 2 autoreceptors, so the effect of adding mirtazapine to a patient stabilized on clonidine may precipitate withdrawal symptoms. [75]
Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]
Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure" refers to the pressure in a brachial artery, where it is most commonly measured.
Severe symptoms include severe increases in heart rate and blood pressure. Temperature may rise to above 41.1 °C (106.0 °F) in life-threatening cases. Other abnormalities include metabolic acidosis, rhabdomyolysis, seizures, kidney failure, and disseminated intravascular coagulation; these effects usually arising as a consequence of hyperthermia.
Some people may also experience high blood pressure while taking Wellbutrin. More serious side effects (though less common) include a risk of seizures or suicidal thoughts.
The tetracyclic antidepressants mianserin and mirtazapine are α 2 blockers, although their efficacy as antidepressants may come from their activity at other receptor sites. [citation needed] Mechanistically, α 2 blockers increase adrenergic, dopaminergic and serotonergic neurotransmitters and induce insulin secretion, decreasing blood sugar ...
"Your blood pressure is supposed to be under 140 over 90, optimally closer to 120 over 80."
In return, you’ll score blood pressure–regulating nutrients like potassium and fiber. Since nutrition can vary from brand to brand, don’t forget to check out the ingredient list and ...
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