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Hydroxocobalamin, also known as vitamin B 12a and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement. [1] As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia. [1] [2] Other uses include treatment for cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Vitamin B 12 deficiencies have a greater effect on young children, pregnant and elderly people, and are more common in middle and lower-developed countries due to malnutrition. [10] The most common cause of vitamin B 12 deficiency in developed countries is impaired absorption due to a loss of gastric intrinsic factor (IF) which must be bound to ...
Vitamin B 12 deficiency is preventable with supplements, which are recommended for pregnant vegetarians and vegans, and not harmful in others. [2] Risk of toxicity due to vitamin B 12 is low. [2] Vitamin B 12 deficiency in the US and the UK is estimated to occur in about 6 percent of those under the age of 60, and 20 percent of those over the ...
Cyanocobalamin is a form of vitamin B 12 used to treat and prevent vitamin B 12 deficiency except in the presence of cyanide toxicity. [7] [8] [2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer.
Again, the daily recommended dietary allowance of vitamin B12 for most adults is 2.4 micrograms, stretching up to 2.6 and 2.8 micrograms if you’re pregnant or nursing.
[10] Because pernicious anemia is due to a lack of intrinsic factor, it is not preventable. [11] Pernicious anemia can be treated with injections of vitamin B 12. [7] If the symptoms are serious, frequent injections are typically recommended initially. [7] There are not enough studies that pills are effective in improving or eliminating ...
“Vitamin B12 requirements are low because we can store up to 2,500 micrograms in the liver,” says Ryan D. Andrews, R.D., C.S.C.S., principal nutritionist at Precision Nutrition. So target just ...
Methylcobalamin is equivalent physiologically to vitamin B 12, [3] and can be used to prevent or treat pathology arising from a lack of vitamin B 12 intake (vitamin B 12 deficiency). Methylcobalamin is also used in the treatment of peripheral neuropathy , diabetic neuropathy , and as a preliminary treatment for amyotrophic lateral sclerosis .