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Magnetic resonance imaging (MRI) scans to assess brain structure, connectivity, and the extent of white matter disease; Positron emission tomography (PET) scans to assess how well the brain uses glucose, and the extent of amyloid plaques and tau tangles. Neuropathological examination if a participant dies and has consented to autopsy.
In contrast to major depression, dementia is a progressive neurodegenerative syndrome involving a pervasive impairment of higher cortical functions resulting from widespread brain pathology. [7] A significant overlap in cognitive and neuropsychological dysfunction in dementia and pseudodementia patients increases the difficulty in diagnosis.
CT scans can expose patients to levels of radiation 100-500 times higher than traditional x-rays, with higher radiation doses producing better resolution imaging. [37] While easy to use, increases in CT scan use, especially in asymptomatic patients, is a topic of concern since patients are exposed to significantly high levels of radiation. [36]
A new study found the biggest risk factors and predictors at 60 for dementia at 80. ... But medical specialists who work with dementia patients say the findings are similar to what they see in ...
Structural MRI scans often reveal frontal lobe and/or anterior temporal lobe atrophy, but in early cases the scan may seem normal. Atrophy can be either bilateral or asymmetric. [ 13 ] Registration of images at different points of time (e.g., one year apart) can show evidence of atrophy that otherwise at individual time points may be reported ...
Parental health, family size and marital history were not significant predictors of dementia. The research highlights the importance of adopting a lifestyle that supports brain health throughout life.
A number of online neuroscience databases are available which provide information regarding gene expression, neurons, macroscopic brain structure, and neurological or psychiatric disorders. Some databases contain descriptive and numerical data, some to brain function, others offer access to 'raw' imaging data, such as postmortem brain sections ...
Dementia is a devastating condition that impacts up to 10 percent of older adults. And while there's no cure, getting diagnosed early can help patients get on a treatment plan and families prepare ...