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It is an uncommon form of Alzheimer's, accounting for only 5–10% of all Alzheimer's cases. About 60% have a positive family history of Alzheimer's and 13% of them are inherited in an autosomal dominant manner. Most cases of early-onset Alzheimer's share the same traits as the "late-onset" form and are not caused by known genetic mutations.
The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) is a brief neuropsychological assessment used to assess the severity of cognitive symptoms of dementia. It is one of the most widely used cognitive scales in clinical trials [ 1 ] and is considered to be the “gold standard” for assessing antidementia treatments.
Compared to late onset dementia, patients with early onset dementia are more likely to have dementias other than Alzheimer's disease, although Alzheimer's is the most common etiology in either case. [13] In general, early onset dementia has a faster progression and features more extensive neurological damage when compared to late onset dementia.
Population growth and aging mean that the number of people with dementia is forecast to reach almost 152.8 million by 2050. There are several forms of dementia, but the most common, Alzheimer’s ...
With increasing clinical focus on dementia, there is likewise increasing interest in pharmacology in the development of drugs to halt, or slow the progression of dementia-related illness such as Alzheimer's Disease. Therefore, early and accurate diagnosis of dementia and staging can be essential to proper clinical care.
A new study distinguishes between two distinct phases of Alzheimer's disease: an early, 'stealth' one without symptoms, and a second phase that aggressively damages the brain.
Alzheimer's disease (AD) is a progressive, degenerative and fatal brain disease, in which cell to cell connections in the brain are lost. Alzheimer's disease is the most common form of dementia. [2] Globally approximately 1–5% of the population is affected by Alzheimer's disease. [3] Women are disproportionately affected by Alzheimer's disease.
Groundbreaking treatments for Alzheimer's disease that work by removing a toxic protein called beta amyloid from the brain may benefit whites more than Black Americans, whose disease may be driven ...