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One theory to explain antidepressant-related weight gain is that psychotropic medications such as antidepressants can affect neurotransmitters involved in eating behavior, causing an increase in ...
TCAs do not block dopamine transport directly but might facilitate dopaminergic effects indirectly by inhibiting dopamine transport into noradrenergic terminals of the cerebral cortex. [29] Because they affect so many different receptors, TCAs have adverse effects, poor tolerability, and an increased risk of toxicity. [2]
Why do antidepressants contribute to weight gain? Science doesn’t yet know, Perlis said. “Remarkably, we don’t know the precise mechanism by which antidepressants contribute to weight changes.
This side effect has been particularly associated with serotonergic antidepressants like SSRIs and SNRIs, but may be less with atypical antidepressants like bupropion, agomelatine, and vortioxetine. [ 77 ] [ 79 ] [ 80 ] Higher doses of antidepressants seem to be more likely to produce emotional blunting than lower doses. [ 77 ]
Monoamine reuptake inhibitors, including DRIs, have proven quite effective in managing excessive food consumption and regulating appetite in obese patients. Though such pharmacotherapy is still available, the majority of stimulant anorectics marketed for this purpose have been withdrawn or discontinued due to adverse side effects such as ...
Popular Over-the-Counter Antidepressant Alternatives. So yes, there are big differences between antidepressants and over-the-counter meds. However, some people definitely think they benefit from ...
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
Tricyclic antidepressants are older antidepressants that, due to their side effect profiles, typically aren’t prescribed as first-line depression treatments today.