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A toxicologist working in a lab (United States, 2008)Toxicology is a scientific discipline, overlapping with biology, chemistry, pharmacology, and medicine, that involves the study of the adverse effects of chemical substances on living organisms [1] and the practice of diagnosing and treating exposures to toxins and toxicants.
Forensic toxicology is a multidisciplinary field that combines the principles of toxicology with expertise in disciplines such as analytical chemistry, pharmacology and clinical chemistry to aid medical or legal investigation of death, poisoning, and drug use. [1]
Forensic chemistry is the application of chemistry and its subfield, forensic toxicology, in a legal setting. A forensic chemist can assist in the identification of unknown materials found at a crime scene. [1] Specialists in this field have a wide array of methods and instruments to help identify unknown substances.
Alexander Oscar Gettler (August 13, 1883 – August 4, 1968) [1] [2] was a toxicologist with the Office of Chief Medical Examiner of the City of New York (OCME) between 1918 and 1959, and the first forensic chemist to be employed in this capacity by a U.S. city. [3] [4] [5] His work at OCME with Charles Norris, the chief medical examiner, created the foundation for modern medicolegal ...
Medical toxicology is a subspecialty of medicine focusing on toxicology and providing the diagnosis, management, and prevention of poisoning and other adverse effects due to medications, occupational and environmental toxicants, and biological agents. [1]
In vitro toxicity testing is the scientific analysis of the toxic effects of chemical substances on cultured bacteria or mammalian cells. [1] In vitro (literally 'in glass') testing methods are employed primarily to identify potentially hazardous chemicals and/or to confirm the lack of certain toxic properties in the early stages of the development of potentially useful new substances such as ...
A toxicologist explains. Meet the expert : Jamie Alan, PhD , an associate professor of pharmacology and toxicology at Michigan State University. What did the study find?
Toxicology testing is commonly conducted during preclinical development for a substance intended for human exposure. Stages of in silico, in vitro and in vivo research are conducted to determine safe exposure doses in model organisms. If necessary, the next phase of research involves human toxicology testing during a first-in-man study.