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There have been 12 large scale, high-quality trials of rtPA in acute ischemic stroke. A meta-analysis of these trials concluded that rtPA given within 6 hours of a stroke significantly increased the odds of being alive and independent at final follow-up, particularly in patients treated within 3 hours.
Alteplase (t-PA) is an effective medication for acute ischemic stroke. When given within 3 hours, treatment with tpa significantly improves the probability of a favourable outcome versus treatment with placebo. [citation needed] The outcome of brain ischemia is influenced by the quality of subsequent supportive care.
Stroke: Thrombolysis reduces major disability or death when given within 3 hours (or perhaps even 6 hours) of ischaemic stroke onset when there are no contraindications to treatment. [2] [3] [4] Massive pulmonary embolism.
UPMC Mercy is a main hospital facility of the University of Pittsburgh Medical Center (UPMC) and is located in the Uptown section of the city of Pittsburgh, Pennsylvania, adjacent to Duquesne University, and a few blocks from the PPG Paints Arena and downtown Pittsburgh.
UPMC St. Margaret is a mid-sized, acute care, teaching community hospital of the University of Pittsburgh Medical Center, located in the Lincoln–Lemington–Belmar neighborhood of Pittsburgh, Pennsylvania, adjacent to the borough of Aspinwall. Situated on 21 acres (8.5 ha), the hospital has 249 beds with more than 800 physicians and 1,500 ...
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New details are emerging about the case against Luigi Mangione, the man indicted on murder charges in the deadly shooting of UnitedHealthcare CEO Brian Thompson in New York City. The 26-year-old ...
Drugmakers plan to raise U.S. prices on at least 250 branded medications including Pfizer COVID-19 treatment Paxlovid, Bristol Myers Squibb's cancer cell therapies and vaccines from France's ...