Search results
Results from the WOW.Com Content Network
Immunofixation tends to replace protein electrophoresis because : [citation needed] it is faster (results within three hours); it is somewhat more sensitive. Immunofixation may reveal an immunoglobulin missed out by protein electrophoresis, especially at low concentrations (less than 1 gram/litre);
Serum protein electrophoresis or immunofixation is positive in 67-100% of cases, while urine protein electrophoresis or immunofixation is positive in 50-100% of cases. [2] Serum free light chain measurement is positive in 100% of cases, evidence that the underlying monoclonal plasma cells secrete free light chains as well as heavy chains.
The serum free light-chain assay in combination with serum protein electrophoresis and serum immunofixation electrophoresis is sufficient to screen for pathological monoclonal plasmaproliferative disorders other than AL amyloidosis which requires all the serum tests as well as 24 h urine immunofixation electrophoresis.
A known amount of standard complement proteins are added to the serum. (These proteins are frequently obtained from guinea pig serum.) The antigen of interest is added to the serum. Sheep red blood cells (sRBCs) [2] which have been pre-bound to anti-sRBC antibodies are added to the serum. The test is considered negative if the solution turns ...
Larger mammals are often preferred as the amount of serum that can be collected is greater. An antigen is injected into the mammal. This induces the B-lymphocytes to produce IgG immunoglobulins specific for the antigen. This polyclonal IgG is purified from the mammal's serum. By contrast, monoclonal antibodies are derived from a single cell line.
A tightly-scripted meeting of the Russia-dominated economic alliance of several ex-Soviet nations briefly went awry Thursday when two leaders engaged in bickering during a live broadcast of the event.
Start by measuring your dog's chest, neck, and length, from his neck to the base of his tail. (Don't include the bottom.) Use a soft tape measure like the ones used for sewing.
Serum immunofixation electrophoresis is 10 times more sensitive than SPEP in the identification of M-proteins in MGRS. [1] Serum protein electrophoresis, urine protein electrophoresis ( UPEP ), serum and urine immunofixation , serum free light chain assay, serum free light chain ratios and a bone marrow biopsy are required for the ...