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An ANA test is considered positive if fluorescence is seen at a titre of 1:40/1:80. Higher titres are more clinically significant as low positives (≤1:160) are found in up to 20% of healthy individuals, especially the elderly. Only around 5% of the healthy population have ANA titres of 1:160 or higher. [8] [53]
Immunofluorescence staining pattern of anti-centromere antibodies on HEp-20-10 cells. ... [2] Main antinuclear antibody patterns on immunofluorescence [3]
An extractable nuclear antigen panel, or an ENA panel, tests for presence of autoantibodies in the blood that react with proteins in the cell nucleus.It is usually done as a follow-up to a positive antinuclear antibody test and when one is showing symptoms of an autoimmune disorder.
18538 Ensembl ENSG00000132646 ENSMUSG00000027342 UniProt P12004 P17918 RefSeq (mRNA) NM_182649 NM_002592 NM_011045 RefSeq (protein) NP_002583 NP_872590 NP_035175 Location (UCSC) Chr 20: 5.11 – 5.13 Mb Chr 2: 132.09 – 132.1 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cryo-EM structure of the DNA-bound PolD–PCNA processive complex Proliferating cell nuclear antigen (PCNA) is ...
Basal bodies originate from and have a substructure similar to that of centrioles, with nine peripheral microtubule triplets (see structure at bottom center of image). A basal body (synonymous with basal granule , kinetosome , and in older cytological literature with blepharoplast ) is a protein structure found at the base of a eukaryotic ...
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An expanding coalition of health and consumer advocates is campaigning against Robert F. Kennedy Jr.'s nomination to the top U.S. health job over concerns about his activism against vaccines and ...