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Aldose reductase activity increases as the glucose concentration rises in diabetes in those tissues that are not insulin sensitive, which include the lenses, peripheral nerves, and glomerulus. Sorbitol does not diffuse through cell membranes easily and therefore accumulates, causing osmotic damage which leads to retinopathy and neuropathy.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Axillary nerve dysfunction is any disorder caused by damage to the axillary nerve. [1] The axillary nerve is a branch of the brachial plexus that innervates the deltoid and teres minor muscles. This nerve can be injured or damaged in a variety of ways - penetrating injury such as knife or gunshot wounds, surgical trauma, stretch injury (common ...
Injury of axillary nerve (axillary neuropathy) is a condition that can be associated with a surgical neck of the humerus fracture. It can also be associated with a dislocated shoulder [ 1 ] or with traction injury to the nerve, which may be caused by over-aggressive stretching or blunt trauma that does not result in fracture or dislocation. [ 2 ]
Some drugs used to treat type 2 diabetes could also help lower a person’s risk of neurodegenerative diseases, such as Alzheimer’s. Image credit: martin-dm/Getty Images.
Injection site reactions (ISRs) are reactions that occur at the site of injection of a drug. They may be mild or severe and may or may not require medical intervention. Some reactions may appear immediately after injection, and some may be delayed. [1] Such reactions can occur with subcutaneous, intramuscular, or intravenous administration.
"I'm playing doctor," Bookless said, describing her foray into the world of do-it-yourself GLP-1 medication, injections developed to control diabetes and now also used for weight loss. Her journey ...
People who have had diabetes for a long time may have kidney damage. Nerve conduction studies Tests to determine nerve function; can detect early neuropathy. Neurologist a physician specializing in diseases of and treatment of the nervous system. Neuropathy nerve damage. In a diabetic context, a chronic complication of diabetes.