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The outbreak of yellow fever in Barcelona in 1821. The evolutionary origins of yellow fever are most likely African. [1] [2] Phylogenetic analyses indicate that the virus originated from East or Central Africa, with transmission between primates and humans, and spread from there to West Africa. [3]
Yellow fever is caused by yellow fever virus (YFV), an enveloped RNA virus 40–50 nm in width, the type species and namesake of the family Flaviviridae. [10] It was the first illness shown to be transmissible by filtered human serum and transmitted by mosquitoes, by American doctor Walter Reed around 1900. [ 32 ]
The family gets its name from the yellow fever virus; flavus is Latin for "yellow", and yellow fever in turn was named because of its propensity to cause jaundice in victims. [3] There are 89 species in the family divided among four genera. [2]
1800–1803 Spain yellow fever epidemic 1800–1803 Spain Yellow fever: 60,000+ [124] 1801 Ottoman Empire and Egypt bubonic plague epidemic 1801 Ottoman Empire, Egypt: Bubonic plague: Unknown [125] 1802–1803 Saint-Domingue yellow fever epidemic 1802–1803 Saint-Domingue: Yellow fever: 29,000–55,000 [126] 1812 Russia typhus epidemic 1812 ...
Flavivirus, renamed Orthoflavivirus in 2023, [3] is a genus of positive-strand RNA viruses in the family Flaviviridae.The genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis, [4] as well as insect-specific flaviviruses (ISFs) such as cell fusing agent virus (CFAV), Palm Creek ...
Yellow fever vaccine is a vaccine that protects against yellow fever. [4] Yellow fever is a viral infection that occurs in Africa and South America. [4] Most people begin to develop immunity within ten days of vaccination and 99% are protected within one month, and this appears to be lifelong. [4]
John James Audubon, famous ornithologist, caught yellow fever on arrival in New York City when he emigrated to the United States in 1803. He died of Alzheimer's disease in 1851. Benjamin Franklin Bache (journalist), died at age 29 in the yellow fever epidemic of 1798 in Philadelphia, Pennsylvania, New Haven, Connecticut and New York City.
The first human virus to be identified was the yellow fever virus. [6] In 1881, Carlos Finlay (1833–1915), a Cuban physician, first conducted and published research that indicated that mosquitoes were carrying the cause of yellow fever, [7] a theory proved in 1900 by commission headed by Walter Reed (1851–1902).