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Skin rash: The most prominent feature is a reddish-purple rash that appears on the lower legs, typically below the knees and above the ankles. The rash is often described as blotchy, mottled, or net-like (reticular in appearance). [6] [7] In some cases, the rash may extend to the dorsum of the feet. [8]
The burning heat is usually limited to the soles of the feet, but may extend up to the ankles or lower legs of some patients. The burning can sometimes be accompanied by feelings of 'pins and needles' or tingling in these regions. Nighttime is when almost all people with this syndrome report the heat symptoms being the worst, with the condition ...
Nicotinamide (INN, BAN UK [2]) or niacinamide (USAN US) is a form of vitamin B 3 found in food and used as a dietary supplement and medication. [3] [4] [5] As a supplement, it is used orally (swallowed by mouth) to prevent and treat pellagra (niacin deficiency). [4]
The Autoimmune Protocol (AIP) diet is an elimination diet designed to help reduce inflammation, manage symptoms and improve quality of life for people with autoimmune diseases.
Ankle pump; Compression stockings; Blood pressure medicine; Hydroxyethylrutoside medication [14] Frequent periods of rest elevating the legs above the heart level; Tilting the bed so that the feet are above the heart. This may be achieved by using a 20 cm (7-inch) bed wedge or sleeping in a 6 degree Trendelenburg position.
The body also converts niacin and the amino acid tryptophan into NAD, says Martens — these are both found in some foods and available as supplements, but may not be as effective.
Primary pellagra is due to a diet that does not contain enough niacin and tryptophan. [1] Secondary pellagra is due to a poor ability to use the niacin within the diet. [1] This can occur as a result of alcoholism, long-term diarrhea, carcinoid syndrome, Hartnup disease, and a number of medications such as isoniazid. [1]
You eat niacin in foods like chicken breast, marinara sauce, salmon, and brown rice, and consuming it helps your body convert the food you eat into energy, she says. But benefits abound when you ...