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Atrial septal defect (ASD) is a congenital heart defect in which blood flows between the atria (upper chambers) of the heart. Some flow is a normal condition both pre-birth and immediately post-birth via the foramen ovale ; however, when this does not naturally close after birth it is referred to as a patent (open) foramen ovale (PFO).
The septum primum is on the left side of the heart in the left atrium while the septum secundum is much thicker and is located on the right side, in the right atrium. During development, blood shunts from the floor of the right atrium through the foramen ovale in the septum secundum then up through the foramen secundum in the septum primum. [2]
The ostium primum atrial septal defect is a defect in the atrial septum at the level of the tricuspid and mitral valves. This is sometimes known as an endocardial cushion defect because it often involves the endocardial cushion, which is the portion of the heart where the atrial septum meets the ventricular septum and the mitral valve meets the tricuspid valve.
An atrial septal defect is a congenital heart defect where the septum between the right and left atrium doesn’t close up all the way and remains open after birth. This causes oxygenated blood to go into pulmonary circulation. One complication from this condition is a paradoxical embolus which crosses from the right to the left side via the ASD.
An Atrial septal defect is a relatively common heart malformation that occurs when the interatrial septum fails to develop properly. Persistence of the ostium secundum is the most common atrial septal defect. [3] Additionally, in a subset of the population, the foramen ovale is not overtly patent but the two septa have not fused.
PFO has long been studied because of its role in paradoxical embolism (an embolism that travels from the venous side to the arterial side). This may lead to a stroke or transient ischemic attack. Transesophageal echocardiography is considered the most accurate investigation to demonstrate a patent foramen ovale. A patent foramen ovale may also ...
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Septal defects that may occur with Lutembacher's syndrome include: Ostium primum atrial septal defect or ostium secundum which is more prevalent. [1] Lutembacher's syndrome affects females more often than males. [1] It can affect children or adults; the person can either be born with the disorder or develop it later in life.