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Paclitaxel, sold under the brand name Taxol among others, is a chemotherapy medication used to treat ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer. [11]
[12] [25] As with all chemotherapy, adverse effects are common, and many side effects have been documented. [17] [19] Because docetaxel is a cell-cycle-specific agent, it is cytotoxic to all dividing cells in the body. [26] This includes tumour cells as well as hair follicles, bone marrow and other germ cells.
Cytoskeletal drugs are small molecules that interact with actin or tubulin.These drugs can act on the cytoskeletal components within a cell in three main ways. Some cytoskeletal drugs stabilize a component of the cytoskeleton, such as taxol, which stabilizes microtubules, or Phalloidin, which stabilizes actin filaments.
Nausea and vomiting are two of the most feared cancer treatment-related side-effects for people with cancer and their families. In 1983, Coates et al. found that people receiving chemotherapy ranked nausea and vomiting as the first and second most severe side-effects, respectively. [98]
They’re great for the neck thanks to their collagen-boosting effects, but because the neck lacks sebaceous glands and is drier, it can be more susceptible to the side effects (think dryness and ...
What are the possible side effects of taking expired vitamins? “There isn’t a promise that the vitamin will pack a full punch if you take it after the expiration date, but there aren’t any ...
Again, this isn't a common side effect. But if you’re experiencing negative mood or personality changes (or any other Ozempic side effects ), talk to your doctor ASAP, say both experts.
It also has antiangiogenic activity through a direct apoptotic effect on endothelial cells. [29] Docetaxel, is a semi-synthetic analogue of paclitaxel, with a trade name Taxotere. Docetaxel has the minimal structure modifications at C13 side chain and C10 substitution showed more water solubility and more potency than paclitaxel.