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A paraganglioma is a rare neuroendocrine neoplasm that may develop at various body sites (including the head, neck, thorax and abdomen). When the same type of tumor is found in the adrenal gland, they are referred to as a pheochromocytoma .
Glomus tumors are usually solitary and small lesions. The vast majority are found in the hand, wrist, foot, and under the fingernails. [3]They are often painful, and the pain is reproduced when the lesion is placed in cold water - a history of sensitivity to cold weather is also common. [6]
Elevated plasma free metanephrines is considered the gold standard diagnosis for pheochromocytoma. [63] Over 10 studies have confirmed that the sensitivity and specificity of this test is 97% and 93% respectively; however, there is still concern for false positive results in the correct clinical scenario. [ 6 ]
M8680/3 paraganglioma, malignant M8681/1 Sympathetic paraganglioma M8682/1 Parasympathetic paraganglioma M8683/0 Gangliocytic paraganglioma (C17.0) M8690/1 Glomus jugulare tumor, NOS (C75.5) Jugular/jugulotympanic paranglioma; M8691/1 Aortic body tumor (C75.5) Aortic/aorticopulmonary paraganglioma; M8692/1 Carotid body tumor/paraganglioma (C75.4)
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