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As melatonin may cause harm in combination with certain medications or in the case of certain disorders, a doctor or pharmacist should be consulted before making a decision to take melatonin. [30] In many countries, melatonin is recognized as a neurohormone and it cannot be sold over-the-counter. [ 66 ]
Even though melatonin is widely considered to be safe and not habit-forming, Dr. Rasgupta says it’s recommended to only take it for short-term use, up to one or two months.
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
Melatonin supplements can lull you to sleep on restless nights, but too much may lead to more rest disruption; here's what sleep experts say about proper dosage for adults and children.
In providing evidence to the ITIA, Swiatek explained that she forgot to include melatonin because it was not on her list of medications and supplements that she would copy across from form to form ...
Large doses of melatonin can even be counterproductive: Lewy et al. [48] provide support to "the idea that too much melatonin may spill over onto the wrong zone of the melatonin phase-response curve." The long-term effects of melatonin administration have not been examined. In some countries, the hormone is available only by prescription or not ...
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