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The open field is an arena with walls to prevent escape. Commonly, the field is marked with a grid and square crossings. The center of the field is marked with a different color to differentiate from the other squares. In the modern open field apparatus, infrared beams or video cameras with associated software can be used to automate the ...
Open field: [38] Rodents tend to avoid brightly illuminated areas, and this avoidance is interpreted as a symptom of anxiety. Open field is a bright enclosure and during the test rodents are placed in this arena thus forcing them to interact with a bright environment. The movement of the experimental subject will be recorded in distance and ...
Laboratory studies of rodents, such as mice and rats, frequently demonstrate positive thigmotaxis. Rodents often prefer to stay close to the walls of an open field or maze, a behavior known as wall-following or thigmotactic behavior. This tendency is utilized in behavioral experiments, such as the open field test, to assess anxiety-like ...
The hole-board test (HBT) is an experimental method used in scientific research to measure anxiety, stress, neophilia and emotionality in animals. [ 1 ] [ 2 ] [ 3 ] Because of its ability to measure multiple behaviors it is a popular test in behavioral pharmacology , but the results are controversial.
The test uses an elevated, plus-shaped (+) apparatus with two open and two enclosed arms. The behavioral model is based on the general aversion of rodents to open spaces. This aversion leads to thigmotaxis : a preference for remaining in enclosed spaces or close to the edges of a bounded space.
The test was first developed by Dr. Carol Barnes in 1979. [1] The test subjects are usually rodents such as mice or lab rats , which either serve as a control or may have some genetic variable or deficiency present in them which will cause them to react to the maze differently.
Enjoy a classic game of Hearts and watch out for the Queen of Spades!
The test was developed to study spatial learning and how it differed from other forms of associative learning. [11] Originally rats, now more commonly mice, were placed in an open pool and the latency to escape was measured for up to six trials a day for 2–14 days. [12] Several variables are used to evaluate an animal's performance.