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In mechanics, strain is defined as relative deformation, compared to a reference position configuration. Different equivalent choices may be made for the expression of a strain field depending on whether it is defined with respect to the initial or the final configuration of the body and on whether the metric tensor or its dual is considered.
Strain means Deformation, and is defined as relative change in length.The Lagrangian formula ε L = (L-L 0)/L 0 = ΔL/L 0, where L 0 is baseline length and L is the resulting length, defines strain in relation to the original length as a dimensionless measure, where shortening will be negative, and lengthening will be positive.
The narrowing of blood vessels leads to an increase in peripheral resistance, thereby elevating blood pressure. While vasoconstriction is a normal and essential regulatory mechanism for maintaining blood pressure and redistributing blood flow during various physiological processes, its dysregulation can contribute to pathological conditions.
Blood viscosity is a measure of the resistance of blood to flow. It can also be described as the thickness and stickiness of blood. This biophysical property makes it a critical determinant of friction against the vessel walls, the rate of venous return, the work required for the heart to pump blood, and how much oxygen is transported to tissues and organs.
Shear stress in a horizontal bar loaded by two offset blocks. Another simple type of stress occurs when a uniformly thick layer of elastic material like glue or rubber is firmly attached to two stiff bodies that are pulled in opposite directions by forces parallel to the layer; or a section of a soft metal bar that is being cut by the jaws of a ...
Tissue factor, FV and FVIII are glycoproteins, and Factor XIII is a transglutaminase. [27] The coagulation factors circulate as inactive zymogens. The coagulation cascade is therefore classically divided into three pathways. The tissue factor and contact activation pathways both activate the "final common pathway" of factor X, thrombin and ...
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Recently, a new mechanosensitive ion channel family was cloned, with two mammalian members, PIEZO1 and PIEZO2. [87] Both these channels are expressed in the lungs and bladder, organs with important mechanosensory functions. Piezo1 is also expressed in the skin, and in red blood cells, and its gain of function mutations cause hereditary ...