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Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant effects. [8] [9] [10] Chemically, it is a substituted amphetamine. [11] Phentermine was approved for medical use in the United States in 1959. [3] It is available as a generic medication. [3]
Phentermine and topiramate was developed by Vivus, a California pharmaceutical company. In December 2009, Vivus, Inc. submitted a new drug application (NDA) to the FDA and on 1 March 2010, Vivus, Inc. announced that the FDA accepted the NDA for review.
Fenfluramine as a single drug was first introduced in the 1970s, but was not popular because it only temporarily reduced weight. [1] A 1984 study found a weight loss of 7.5 kg on average in 24 weeks, as compared to 4.4 kg under placebo. [4]
Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic.It is 30 to 50 times more potent than heroin and 100 times more potent than morphine; [11] its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries.
Bupropion, formerly called amfebutamone, [16] and sold under the brand name Wellbutrin among others, is an atypical antidepressant that is US FDA-approved to treat major depressive disorder, seasonal affective disorder and to support smoking cessation.
These women, however, still maintained the "hourglass" shape with its relationship to fertility. [239] During the 19th century, views on obesity changed in the Western world. After centuries of obesity being synonymous with wealth and social status, slimness began to be seen as the desirable standard. [ 20 ]
The fight card was headlined by a bout between top contenders, returning Vitor Belfort, and Chuck Liddell.UFC 37.5 was the first UFC event to feature Joe Rogan as a color commentator but he would leave again to host Fear Factor, and return at UFC 40.
37.5°C no Namida (37.5°Cの涙, lit. "37.5°C Tears") is a Japanese manga series written and illustrated by Chika Shiina. It was serialized in Shogakukan's Cheese! magazine from October 2013 to May 2022, with twenty-four tankōbon volumes compiling the chapters released from March 2014 to 2022.