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Ipratropium bromide/salbutamol, sold under the brand name Combivent among others, is a combination medication used to treat chronic obstructive pulmonary disease (COPD). [1] [4] [5] It contains ipratropium (an anticholinergic) and salbutamol (albuterol, a β 2-adrenergic agonist). [1] Common side effects include sore throat, muscle cramps, and ...
Ipratropium is a derivative of atropine [3] but is a quaternary amine and therefore does not cross the blood–brain barrier, which prevents central side effects. Ipratropium should never be used in place of salbutamol (albuterol) as a rescue medication.
Salbutamol, also known as albuterol and sold under the brand name Ventolin among others, [1] is a medication that opens up the medium and large airways in the lungs. [8] It is a short-acting β 2 adrenergic receptor agonist that causes relaxation of airway smooth muscle . [ 8 ]
Some examples of anticholinergics are tiotropium (Spiriva) and ipratropium bromide. [citation needed] Tiotropium is a long-acting, 24-hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Only available as an inhalant, ipratropium bromide is used in the treatment of asthma and COPD.
[1] [2] It is a combination of salbutamol sulfate (albuterol sulfate), a short-acting beta2-adrenergic agonist, and budesonide, an inhaled corticosteroid. [1] [2] It is inhaled using a pressurized metered-dose inhaler. [1] [2] The most common side effects include headache, oral candidiasis, cough, and difficulty speaking. [2]
There can be side effects from supplementation, such as bad-smelling breath and sweat and headaches, as well as digestive issues such as heartburn, nausea or diarrhea, Harvard’s site stated.
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Rarer side effects may indicate a dangerous allergic reaction. These include: paradoxical bronchospasm (shortness of breath and difficulty breathing); skin itching, rash, or hives ( urticaria ); swelling ( angioedema ) of any part of the face or throat (which can lead to voice hoarseness ), or swelling of the extremities.
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