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Dennis Joseph Slamon (born August 6, 1948), [1] [2] is an American oncologist and chief of the division of Hematology-Oncology at UCLA.He is best known for his work identifying the HER2/neu oncogene that is amplified in 25–33% of breast cancer patients and the resulting treatment trastuzumab.
It has been found that patients with ER+ (Estrogen receptor positive)/HER2+ compared with ER-/HER2+ breast cancers may actually benefit more from drugs that inhibit the PI3K/AKT molecular pathway. [37] Over-expression of HER2 can also be suppressed by the amplification of other genes.
The USA Today critic wrote:"'Living Proof' knows its target audience, though, and appeals to it with an earnestness made more engaging by a string of winning performances. Connick sustains the breezy charm he has shown as an actor and musician, but also shows a decided urgency in tracing Slamon's often frustrating, sometimes desperate struggle ...
A Pennsylvania mom convicted in the hanging murders of her two young children was sentenced to prison, according to multiple reports.. According to NBC News, the Reading Eagle and WPVI, 41-year ...
Neratinib was discovered and initially developed by Wyeth; Pfizer continued development up to Phase III in breast cancer, and licensed it to Puma Biotechnology in 2011. [ 12 ] It was approved for medical use in the United States in July 2017, for the extended adjuvant treatment of adults with early stage HER2 -overexpressed/amplified breast ...
Patrick told her he’d already found a later one to attend. He had it covered. Anne and Jim kept working on a Plan B. Anne was worried that her son hadn’t found a sponsor yet, so she called a friend in AA; he promised to help get Patrick a sponsor after the weekend, when he’d be back in town. Jim called doctors to see if they prescribed ...
Emily Rosa (born February 6, 1987) is the youngest person to have a research paper published in a peer reviewed medical journal. At age nine Rosa conceived and executed a scientific study of therapeutic touch which was published in the Journal of the American Medical Association in 1998.
Each episode begins with a poem or lyric pertaining to the subject of the show, followed by Brule crediting the work but usually mispronouncing the author's name; his mispronunciations are a staple of the show—in the first episode, he mispronounced the name of nutritionist Dr. Johnny Bowden [3] both as "Dr. Jimmy Brungus" and "Dr. Jungy Brungan".