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Ketamine infusions have been a game-changer for many with treatment-resistant depression and other mental health issues. But when Matthew Perry died from “acute effects of ketamine” a year ago ...
But Feifel said the drug’s dissociative and hallucinogenic properties — which made it such a popular party drug — may hold the key to why it helps some people with depression and other ...
A legal medication commonly used medically as an anesthetic, ketamine has been increasingly offered “off label” at private clinics in an effort to treat depression and other mental health ...
Ketamine crystals on a glass plate. K-hole is the feeling of getting a high enough dose of ketamine to experience a state of dissociation.This intense detachment from reality is often a consequence of accidental overconsumption of ketamine; however, some users consciously seek out the k-hole as they find the powerful dissociative effects to be quite pleasurable and enlightening.
A meta-analysis of 43 research studies looking at psychedelics for use in mental health treatment found that 59% of the studies reported that at least one participant with a mild adverse effect of taking psychedelics; however, none of these situations required medical interventions. [27]
Ketamine potentiates the sedative effects of propofol [85] and midazolam. [86] Naltrexone potentiates psychotomimetic effects of a low dose of ketamine, [87] while lamotrigine [38] and nimodipine [39] decrease them. Clonidine reduces the increase of salivation, heart rate, and blood pressure during ketamine anesthesia and decreases the ...
Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety, obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [1]
Last fall, the FDA put out a warning on some types of ketamine, saying the drug is not approved for any psychiatric disorder and warned about taking it at home, which can be even more risky ...