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  2. Allopurinol - Wikipedia

    en.wikipedia.org/wiki/Allopurinol

    Common side effects when used orally include itchiness and rash. [7] Common side effects when used by injection include vomiting and kidney problems. [7] While not recommended historically, starting allopurinol during an attack of gout appears to be safe. [8] [9] In those already on the medication, it should be continued even during an acute ...

  3. Allopurinol hypersensitivity syndrome - Wikipedia

    en.wikipedia.org/wiki/Allopurinol...

    Allopurinol hypersensitivity syndrome (AHS) typically occurs in persons with preexisting kidney failure. [3]: 119 Weeks to months after allopurinol is begun, the patient develops a morbilliform eruption [3]: 119 or, less commonly, develops one of the far more serious and potentially lethal severe cutaneous adverse reactions viz., the DRESS syndrome, Stevens Johnson syndrome, or toxic epidermal ...

  4. Febuxostat - Wikipedia

    en.wikipedia.org/wiki/Febuxostat

    It is generally recommended only for people who cannot take allopurinol. [8] [9] It is taken by mouth. [7] Common side effects include liver problems, nausea, joint pain, and a rash. [7] Serious side effects include an increased risk of death as compared with allopurinol, Stevens–Johnson syndrome, and anaphylaxis.

  5. Probenecid - Wikipedia

    en.wikipedia.org/wiki/Probenecid

    Mild symptoms such as nausea, loss of appetite, dizziness, vomiting, headache, sore gums, or frequent urination are common with this medication. Life-threatening side effects such as thrombocytopenia, hemolytic anemia, leukemia and encephalopathy are extremely rare. [4] Theoretically probenecid can increase the risk of uric acid kidney stones.

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  7. Severe cutaneous adverse reactions - Wikipedia

    en.wikipedia.org/wiki/Severe_cutaneous_adverse...

    Allopurinol and sulfasalazine account for almost 66% of DRESS syndrome cases with minocycline being the third most common cause of the disorder; Strontium ranelate, leflunomide, dapsone, and nonsteroidal anti-inflammatory drugs (diclofenac, celecoxib, ibuprofen, and phenylbutazone) are less common causes of the disorder.

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  9. Tumor lysis syndrome - Wikipedia

    en.wikipedia.org/wiki/Tumor_lysis_syndrome

    Allopurinol (a xanthine oxidase inhibitor, which inhibits uric acid production) works by preventing the formation of uric acid following tumor cell lysis. [4] [13] Rasburicase is a synthetic urate oxidase enzyme and acts by degrading uric acid. No current guidelines endorse the concurrent use of allopurinol and rasburicase.

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