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The metabolic cost of transport includes the basal metabolic cost of maintaining bodily function, and so goes to infinity as speed goes to zero. [1] A human achieves the lowest cost of transport when walking at about 6 kilometres per hour (3.7 mph), at which speed a person of 70 kilograms (150 lb) has a metabolic rate of about 450 watts. [1 ...
The effect of gait parameters on energetic cost is a relationship that describes how changes in step length, cadence, step width, and step variability influence the mechanical work and metabolic cost involved in gait. The source of this relationship stems from the deviation of these gait parameters from metabolically optimal values, with the ...
It is also common to measure the cost of transport (COT), or the energetic cost to travel a given distance, in order to make comparisons of economy between individuals. Because this value is thought to remain constant across speed, the measurement of the COT at any single fixed submaximal speed is thought to provide an adequate representation ...
Cori cycle. The Cori cycle (also known as the lactic acid cycle), named after its discoverers, Carl Ferdinand Cori and Gerty Cori, [1] is a metabolic pathway in which lactate, produced by anaerobic glycolysis in muscles, is transported to the liver and converted to glucose, which then returns to the muscles and is cyclically metabolized back to lactate.
ASL, δ-crystallin, class II fumarase, aspartase, adenylosuccinase lyase, and 3-carboxy-cis and cis-muconate lactonizing enzyme are all members of the same homotetrameric superfamily of enzymes, in which most catalyze the same type of elimination reactions where a C-O or C-N bond is broken and fumarate is released as a product. δ-crystallins ...
Major metabolic pathways in metro-style map. Click any text (name of pathway or metabolites) to link to the corresponding article. Click any text (name of pathway or metabolites) to link to the corresponding article.
The new metabolic pathway consists of mitochondrial transport proteins and several enzymes, including ATP-citrate lyase (ACLY) and malate dehydrogenases 1 and 2 (MDH1 and MDH2). The proposed metabolic pathway may explain the Warburg effect – that cancer cells produce energy through a suboptimal pathway – and hypoxia in cancer.
SEE-II models much of its sign vocabulary from American Sign Language (ASL), but modifies the handshapes used in ASL in order to use the handshape of the first letter of the corresponding English word. [2] SEE-II is not considered a language itself like ASL; rather it is an invented system for a language—namely, for English. [3] [4]