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  2. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  3. Fractional excretion of sodium - Wikipedia

    en.wikipedia.org/wiki/Fractional_excretion_of_sodium

    Fractional excretion of other substances can be measured to determine kidney clearance including urea, uric acid, and lithium. These can be used in patients undergoing diuretic therapy, since diuretics induce a natriuresis. Thus, the urinary sodium concentration and FE Na may be higher in patients receiving diuretics in spite of prerenal ...

  4. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    At the same time, loop diuretics inhibit the tubuloglomerular feedback mechanism so that increase in salts at the lumen near macula densa does not trigger a response that reduces the GFR. [6] Loop diuretics also inhibit magnesium and calcium reabsorption in the thick ascending limb. Absorption of magnesium and calcium are dependent upon the ...

  5. Chlortalidone - Wikipedia

    en.wikipedia.org/wiki/Chlortalidone

    Chlortalidone is considered a first-line medication for treatment of high blood pressure. [2] Some recommend chlortalidone over hydrochlorothiazide. [1] [15] A meta-analysis of randomized controlled trials found that chlortalidone is more effective than hydrochlorothiazide for lowering blood pressure, while the two drugs have similar toxicity.

  6. Metolazone - Wikipedia

    en.wikipedia.org/wiki/Metolazone

    Metolazone and a loop diuretic will synergistically enhance diuresis over the use of either agent alone. Using this combination, diuretic effects will occur at two different segments of the nephron; namely, the loop diuretic will act at the loop of Henle, and metolazone will act at the distal convoluted tubule. Metolazone is frequently ...

  7. Factbox-Donald Trump's lawsuits against media companies - AOL

    www.aol.com/news/factbox-donald-trumps-lawsuits...

    U.S. President-elect Donald Trump is making good on his threats to go after the media in court, with several recent lawsuits seeking damages against major publishers over what he describes as ...

  8. We all need HGH, the hormone responsible for growth. What ...

    www.aol.com/hgh-hormone-responsible-growth...

    Most people naturally have enough HGH. For those with a growth hormone deficiency (or a few other health conditions), GH therapy may offer a solution.

  9. Triamterene - Wikipedia

    en.wikipedia.org/wiki/Triamterene

    Triamterene directly blocks the epithelial sodium channel [4] (ENaC) on the lumen side of the kidney collecting tubule. [5]: 127 Other diuretics cause a decrease in the sodium concentration of the forming urine due to the entry of sodium into the cell via the ENaC, and the concomitant exit of potassium from the principal cell into the forming urine.

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