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DESeq2 is a software package in the field of bioinformatics and computational biology for the statistical programming language R. It is primarily employed for the analysis of high-throughput RNA sequencing (RNA-seq) data to identify differentially expressed genes between different experimental conditions.
Within computational biology, an MA plot is an application of a Bland–Altman plot for visual representation of genomic data. The plot visualizes the differences between measurements taken in two samples, by transforming the data onto M (log ratio) and A (mean average) scales, then plotting these values.
Canonical form – Standard representation of a mathematical object; Graph canonization – Unsolved problem in computational complexity theory; Lemmatisation – Natural language processing canonicalisation; Text normalization – Process of transforming text into a single canonical form
fastqp Simple FASTQ quality assessment using Python. Kraken: [9] A set of tools for quality control and analysis of high-throughput sequence data. HTSeq [10] The Python script htseq-qa takes a file with sequencing reads (either raw or aligned reads) and produces a PDF file with useful plots to assess the technical quality of a run.
The code above uses OCaml's default hash function Hashtbl.hash, which is defined automatically for all types. To use a modified hash function, use the functor interface Hashtbl.Make to create a module, such as with Map. Finally, functional maps (represented as immutable balanced binary trees): #
Without normalization, the clusters were arranged along the x-axis, since it is the axis with most of variation. After normalization, the clusters are recovered as expected. In machine learning, we can handle various types of data, e.g. audio signals and pixel values for image data, and this data can include multiple dimensions. Feature ...
In the simplest cases, normalization of ratings means adjusting values measured on different scales to a notionally common scale, often prior to averaging. In more complicated cases, normalization may refer to more sophisticated adjustments where the intention is to bring the entire probability distributions of adjusted values into alignment.
In bioinformatics, sequence analysis is the process of subjecting a DNA, RNA or peptide sequence to any of a wide range of analytical methods to understand its features, function, structure, or evolution. It can be performed on the entire genome, transcriptome or proteome of an organism, and can also involve only selected segments or regions ...