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2. List of 5α-reductase inhibitors - Wikipedia

   en.wikipedia.org/wiki/List_of_5α-reductase...

   This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...

3. Comparison of bicalutamide with other antiandrogens

   en.wikipedia.org/wiki/Comparison_of_bicalutamide...

   Unlike spironolactone, bicalutamide has no antimineralocorticoid activity, [97] and for this reason, has no risk of hyperkalemia (which can, rarely/in severe cases, result in hospitalization or death) [112] or other antimineralocorticoid side effects such as urinary frequency, dehydration, hypotension, hyponatremia, metabolic acidosis, or ...

4. How Effective Is Saw Palmetto as a Hair Loss Treatment? - AOL

   www.aol.com/effective-saw-palmetto-hair-loss...

   Powder vs. Liquid Saw Palmetto Supplementation. ... 5-alpha reductase inhibitors like finasteride prevent the conversion of testosterone to DHT. ... Spironolactone, another blood pressure ...

5. 5α-Reductase inhibitor - Wikipedia

   en.wikipedia.org/wiki/5α-reductase_inhibitor

   Thus, inhibition results in decreased amounts of DHT. Because of this, slight elevations in testosterone and estradiol levels occur. [36] The 5α-reductase reaction is a rate-limiting step in the testosterone reduction and involves the binding of NADPH to the enzyme followed by the substrate. [4] [37] Substrate + NADPH + H + → 5α-substrate ...

6. DHT Blockers for Hair Loss: 4 Things to Know - AOL

   www.aol.com/dht-blockers-hair-loss-4-115800682.html

   Researchers believe that men affected by androgenetic alopecia tend to have higher levels of the 5-alpha-reductase enzyme, which converts testosterone into DHT, as well as an increased level of ...

7. Can Finasteride Lower Testosterone? (& Other Potential Side ...

   www.aol.com/finasteride-lower-testosterone-other...

   Bonus: It doesn’t have any significant adverse effects or cause observed changes to serum-free testosterone. Saw palmetto. Saw palmetto is used for a variety of conditions, and hair loss is one ...